In 1961, the first four Canadian missionaries were sent to Brazil on the invitation of Bishop Marie-Joseph Lemieux, OP. He hoped for some form of collaboration between the Sisters and priests from the dioceses of Ottawa, Hull and Mont-Laurier working at that time in the diocese of Marília, in São Paulo. After an intensive Portuguese language course in Marília, they settled in the city of Tupi Paulista, in the State of São Paulo. They began working at the Santa Casa Hospital in Tupi Paulista and became involved in the parish. Later, they took care of the elderly at Asilo São Vincente de Paulo which was located in the same city.
In 1962, with additional Canadian missionaries being added to their number and new Brazilian Sisters joining the community, they proceeded with the building of Sainte-Marie Convent in Tupi Paulista, as well as opening other houses in the following regions: Panorama, Pau Dalho, Monte Castelo and Junqueirópolis.
In 1965, a new mission was begun in the Vila Fatima sector of the city of Guarulhos, on the outskirts of São Paulo. One year later, this mission was transferred to the Bom Clima sector, in Cocaia. Here the Sisters were mostly involved in the diocese.
The year 1982 saw the first steps of the mission in Ferraz de Vasconcelos, in the State of São Paulo, where the Sisters were involved in parish pastoral and social work until 2011.
To this day, the Sisters respond to several calls from different areas. Once their mission is complete, they leave one area to go where the needs are more pressing. They have gone to help in the State of Minas Gerais at Ouro Preto, at Monte Azul, at Belo Horizonte, at Ninhera, at Taiobeiras and at Lafaiete, in the State of Bahia, at Barreiras, in the State of São Paulo, at Santa Bárbara d’Oeste, at Sapopemba, at Parada Inglesa and in the Macedo sector, in Guarulhos where, since 2011, we find the new Regional House and the Centro de Espiritulidade Élisabeth Bruyère.